Triggering Receptor Expressed on Myeloid Cells-1

An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.

Also Known As:

CD354 Antigen; TREM-1 Protein; Antigen, CD354; TREM 1 Protein; Triggering Receptor Expressed on Myeloid Cells 1

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Triggering Receptor Expressed on Myeloid Cells-1: 376
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Triggering Receptor Expressed on Myeloid Cells-1: 376
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Triggering Receptor Expressed on Myeloid Cells-1: 376
    - Cell Surface Receptors: 2156
      - Immunologic Receptors: 10
        Triggering Receptor Expressed on Myeloid Cells-1: 376

Pol Le Renard Selected Research

Pol Le Renard Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure